‘Leaky’ muscle fibers drive immune response in muscular dystrophy

A Northwestern Medicine study has uncovered how chronic defects in muscle membrane repair can fuel harmful inflammation. The findings offer new details on an essential biological process and may be useful in understanding certain forms of muscular dystrophy, said Elizabeth McNally, MD, Ph.D., the Elizabeth J. Ward Professor of Genetic Medicine, director of the Center for Genetic Medicine, and co-senior author of the study published in JCI Insight.

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